Liverpool will look to bounce back from their Champions League disappointment when they return to domestic action against Newcastle United.
Jurgen Klopp's side have the chance to go back to the top of the table if they secure victory at St James' Park, putting the pressure on defending champions Manchester City in the process.
888Sport go 1/3 (1.33) about a Reds win. That would be an eighth consecutive league victory, but they remain 7/2 (4.50) shots to end the season in first place.
The Magpies have been tricky opposition for the Merseyside club in recent years though; Rafa Benitez's side have only lost one of their last seven home Premier League games against Liverpool.
Indeed, Newcastle have won six of their last seven home games in this competition, yet they are 17/2 (9.50) outsiders to come out on top this weekend. 888Sport go 21/5 (5.20) about the pair sharing the spoils.
Regardless of the outcome at St James' Park, all eyes will turn to Manchester on Monday night.
Pep Guardiola's side should be fresh for their meeting with Leicester City and the Citizens are just 1/7 (1.14) to win a 13th straight Premier League match. They remain firm favourites for the title at 1/5 (1.20) too.
The Foxes already boast one win over the defending champions this season though, emerging victorious at the King Power Stadium in December. Brendan Rodgers' side are looking for a top-flight double over Manchester City for the first time since the 1986-87 campaign.
Liverpool backers will hope that Leicester can cause Guardiola's side more problems. Only against Chelsea (3) has the Spaniard lost more games in this competition since taking over at the Etihad Stadium.
Despite that, the visitors are rank outsiders at 17/1 (18.0) with 888Sport to pull off a shock victory and even the draw is a 15/2 (8.50) chance.
If Leicester are to make an impact in the final third, Jamie Vardy is likely to be the Foxes' most potent attacking threat.
Since his Premier League debut the 32-year-old striker has 31 goals against the "Big Six" teams including a double against Arsenal last time out and he's an industry-best price of 3/1 (4.0) to find the net in this one.
Get the latest Premier League odds with 888Sport
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